Description

4-Bromobenzo[D]Oxazol-2-Amine is a high-purity brominated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce the 2-aminobenzoxazole pharmacophore into target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly those targeting kinase inhibition or acting as modulators for various biological receptors.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides that require the benzoxazole core for bioactivity.
• Material Science Research: Serves as a precursor for organic light-emitting diodes (OLEDs), liquid crystals, and other functional organic materials due to its electron-rich heterocyclic structure.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes, tags, and activity-based protein profiling (ABPP) reagents.
• Academic & Contract Research: Essential for methodological studies in organic chemistry, including palladium-catalyzed cross-coupling reactions and heterocycle functionalization.
• Dye & Pigment Industry: Acts as an intermediate for synthesizing specialized dyes and optical brighteners.

Basic Information

Product Name	4-Bromobenzo[D]Oxazol-2-Amine
CAS No.	1806340-56-6
Molecular Formula	C7H5BrN2O
Molecular Weight	213.03 g/mol
Synonyms	4-Bromo-1,3-benzoxazol-2-amine; 4-Bromo-2-aminobenzoxazole; 2-Amino-4-bromobenzoxazole; 4-Bromobenzo[d]oxazol-2-amine; 4-Bromo-2-benzoxazolamine; 1806340-56-6; 4-Br-BOA
EINECS	Contact for details

Quality Control

Our 4-Bromobenzo[D]Oxazol-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.