Description

4,4,4-Trifluoro-1-(Quinolin-6-Yl)Butane-1,3-Dione is a specialized fluorinated diketone building block featuring a quinoline heterocycle. This compound is valued for its unique molecular architecture, which combines a trifluoromethyl group with a β-diketone motif and a nitrogen-containing aromatic system, making it a versatile intermediate in advanced synthesis. It is primarily sought by researchers and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients, particularly in medicinal chemistry for drug discovery programs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in the development of kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in creating new active ingredients for crop protection products, leveraging the stability and bioactivity imparted by the fluorine atoms.
• Material Science Precursor: Serves as a monomer or ligand precursor for developing advanced fluorinated polymers or metal-organic frameworks (MOFs) with specific electronic properties.
• Chemical Synthesis: Acts as a versatile reagent in organic synthesis for constructing complex heterocyclic systems via cyclization and condensation reactions.
• Ligand in Catalysis: The β-diketone moiety can chelate metals, making it useful for developing catalysts in asymmetric synthesis and cross-coupling reactions.

Basic Information

Product Name	4,4,4-Trifluoro-1-(Quinolin-6-Yl)Butane-1,3-Dione
CAS No.	1805709-11-8
Molecular Formula	C₁₃H₈F₃NO₂
Molecular Weight	267.21 g/mol
Synonyms	6-(4,4,4-Trifluoro-3-oxobutanoyl)quinoline; 1-(6-Quinolyl)-4,4,4-trifluorobutane-1,3-dione; 4,4,4-Trifluoro-1-(6-quinolyl)-1,3-butanedione; 4,4,4-Trifluoro-1-(quinolin-6-yl)butane-1,3-dione; TFBQ; Quinolin-6-yl trifluoromethyl diketone
EINECS	Contact for details

Quality Control

Our 4,4,4-Trifluoro-1-(Quinolin-6-Yl)Butane-1,3-Dione is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent identity. A Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.