Description

6-Bromo-5-(trifluoromethyl)nicotinic acid is a high-value, multi-functional heterocyclic building block characterized by its bromine and trifluoromethyl substituents. This compound is essential for medicinal chemistry and agrochemical research, enabling the rapid synthesis of novel molecules with enhanced biological activity and metabolic stability. It is primarily sought after by pharmaceutical R&D teams, agrochemical innovators, and advanced material scientists for constructing complex target molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors, antiviral agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group improves lipophilicity and bioactivity.
• Material Science Research: Serves as a precursor for functionalized ligands and organic semiconductors in electronic and optoelectronic devices.
• Chemical Biology Probes: Employed in the design of molecular probes and tags for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	6-Bromo-5-(trifluoromethyl)nicotinic Acid
CAS No.	1805579-11-6
Molecular Formula	C7H3BrF3NO2
Molecular Weight	269.00 g/mol
Synonyms	5-(Trifluoromethyl)-6-bromonicotinic acid; 6-Bromo-5-trifluoromethylpyridine-3-carboxylic acid; 3-Bromo-2-(trifluoromethyl)pyridine-5-carboxylic acid; 2-Bromo-3-(trifluoromethyl)pyridine-5-carboxylic acid; 6-Bromo-5-(trifluoromethyl)-3-pyridinecarboxylic acid; Nicotinic acid, 6-bromo-5-(trifluoromethyl)-; 1805579-11-6
EINECS	Contact for details

Quality Control

Every batch of 6-Bromo-5-(trifluoromethyl)nicotinic acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.