Description

2-Bromo-5-Fluoro-4-Nitro-Benzoic Acid Methyl Ester is a high-value, multi-functional aromatic building block essential for advanced organic synthesis. Its unique halogenated and nitrated structure makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing halogen and nitro functional groups.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the bromo-fluoro-nitro substitution pattern is advantageous.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic materials.
• Ligand Synthesis: Building block for creating complex ligands used in catalysis and metal-organic frameworks (MOFs).
• Dye and Pigment Intermediate: Employed in the synthesis of specialized colorants and imaging agents.
• Academic & Industrial R&D: A versatile reagent for method development and exploratory chemistry in synthetic laboratories.

Basic Information

Product Name	2-Bromo-5-Fluoro-4-Nitro-Benzoic Acid Methyl Ester
CAS No.	1805503-91-6
Molecular Formula	C8H5BrFNO4
Molecular Weight	278.03 g/mol
Synonyms	Methyl 2-Bromo-5-Fluoro-4-Nitrobenzoate; 2-Bromo-5-Fluoro-4-Nitrobenzoic Acid Methyl Ester; Benzoic acid, 2-bromo-5-fluoro-4-nitro-, methyl ester; Methyl 2-bromo-5-fluoro-4-nitrobenzoate; 1805503-91-6; 2-Bromo-5-fluoro-4-nitro-benzoic acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-5-Fluoro-4-Nitro-Benzoic Acid Methyl Ester is manufactured and tested under strict quality management systems. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles to ensure it meets the exacting standards required for research and commercial synthesis. Our quality commitment supports compliance with cGMP and ICH guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider maintaining under an inert atmosphere such as nitrogen or argon to preserve stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.