Description

5-Cyclopropyl-1H-Imidazol-2-Amine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS number 1803598-15-3. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring imidazole-based scaffolds. It is essential for research and development chemists and process scale-up teams in the pharmaceutical and biotechnology sectors. The compound's defined structure enables precise molecular modifications, supporting the development of targeted drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition or other enzyme-related pathways.
• Biochemical Research: Used as a standard or reagent in medicinal chemistry research for structure-activity relationship (SAR) studies.
• Agrochemical Development: Serves as a building block for creating new fungicides or herbicides that leverage the imidazole moiety for biological activity.
• Organic Synthesis: Employed in academic and industrial laboratories for constructing complex heterocyclic compounds.
• Ligand Synthesis: Potential use in creating specialized ligands for catalysis or metal-organic frameworks (MOFs).

Basic Information

Product Name	5-Cyclopropyl-1H-Imidazol-2-Amine Hydrochloride
CAS No.	1803598-15-3
Molecular Formula	C6H10ClN3
Molecular Weight	159.62 g/mol
Synonyms	2-Amino-5-cyclopropyl-1H-imidazole hydrochloride; 5-Cyclopropyl-1H-imidazol-2-amine HCl; 5-Cyclopropyl-2-imidazolamine hydrochloride; 1H-Imidazol-2-amine, 5-cyclopropyl-, hydrochloride; 1803598-15-3; 5-Cyclopropyl-1H-imidazol-2-amine monohydrochloride
EINECS	Contact for details

Quality Control

Our 5-Cyclopropyl-1H-Imidazol-2-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.