Description

4-Ethynylcyclohexan-1-Amine Hydrochloride is a versatile and highly functionalized organic building block. This compound is valued for its dual functional groups—a primary amine and an alkyne—which enable its use in advanced synthetic transformations, particularly in click chemistry and bioconjugation. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and material science industries for the synthesis of novel active ingredients, ligands, and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting central nervous system (CNS) disorders.
• Bioconjugation & Probe Development: The alkyne moiety enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) for labeling biomolecules, developing diagnostic probes, and creating antibody-drug conjugates (ADCs).
• Material Science & Polymer Chemistry: Serves as a monomer or cross-linking agent for creating specialty polymers, dendrimers, and smart materials with tailored properties.
• Agrochemical Research: Used in the research and development of new crop protection agents and plant growth regulators.
• Catalyst & Ligand Synthesis: Precursor for creating novel chiral amines and ligands used in asymmetric catalysis.
• Academic & Contract Research: Essential reagent in university and CRO laboratories for methodological development and exploring new chemical spaces.

Basic Information

Product Name	4-Ethynylcyclohexan-1-Amine Hydrochloride
CAS No.	1803593-39-6
Molecular Formula	C8H14ClN
Molecular Weight	159.66 g/mol
Synonyms	4-Ethynylcyclohexylamine hydrochloride; 4-Ethynyl-1-cyclohexanamine hydrochloride; 1-Amino-4-ethynylcyclohexane hydrochloride; 4-Ethynylcyclohexanamine HCl; Cyclohexanamine, 4-ethynyl-, hydrochloride; trans-4-Ethynylcyclohexan-1-amine hydrochloride; cis-4-Ethynylcyclohexan-1-amine hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Ethynylcyclohexan-1-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.