Description

3-Cyclopropyl-Dl-Alanine Hcl is a non-natural, cyclopropyl-substituted amino acid derivative, serving as a critical chiral building block in advanced organic synthesis. Its unique constrained ring structure is essential for modulating the biological activity, metabolic stability, and conformational properties of target molecules. This high-purity intermediate is primarily sought after by pharmaceutical R&D and fine chemical manufacturers for the development of novel active pharmaceutical ingredients (APIs), peptide mimetics, and agrochemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and synthesis of novel drug candidates, particularly in areas targeting central nervous system (CNS) disorders and infectious diseases.
• Peptidomimetics Development: Used to introduce conformational constraints into peptide backbones, enhancing stability against enzymatic degradation and improving receptor selectivity.
• Agrochemical Synthesis: Employed in the creation of advanced herbicides and fungicides, where the cyclopropyl group can contribute to unique modes of action.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies and as a standard in analytical method development for amino acid analysis.
• Ligand and Catalyst Design: Utilized in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	3-Cyclopropyl-Dl-Alanine Hcl
CAS No.	1803567-60-3
Molecular Formula	C₆H₁₁NO₂·HCl
Molecular Weight	165.62 g/mol (Free base: 129.16)
Synonyms	DL-3-Cyclopropylalanine hydrochloride; (±)-3-Cyclopropylalanine HCl; 2-Amino-3-cyclopropylpropanoic acid hydrochloride; Cyclopropanealanine HCl; 3-Cyclopropyl-DL-alanine hydrochloride; (RS)-3-Cyclopropylalanine hydrochloride; α-Amino-β-cyclopropylpropionic acid HCl
EINECS	Contact for details

Quality Control

Our 3-Cyclopropyl-Dl-Alanine Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via IR and NMR spectroscopy. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP starting material requirements. Specifications are aligned with industry standards for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the original container must be kept sealed under an inert atmosphere after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	DL-Ratio ~50:50
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.