Description

Cyclobutanamine, 2,2-Dimethyl-, Hydrochloride (1:1) is a high-purity, functionalized amine hydrochloride salt, a key building block in advanced organic synthesis. This compound matters for its role as a versatile chiral intermediate, enabling the construction of complex molecular architectures with precise stereochemistry. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers developing novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials where structural complexity and purity are critical.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and metabolic disorder drug candidates.
• Agrochemical Synthesis: Serves as a building block for creating advanced, high-efficacy pesticides and herbicides with tailored biological activity.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Peptidomimetics Research: Incorporated into the backbone of peptide analogs to enhance metabolic stability and bioavailability.
• Material Science: A monomer or modifier in the synthesis of specialty polymers and functionalized surfaces.
• Academic & Industrial R&D: Employed in methodological studies and process chemistry for constructing strained ring systems.

Basic Information

Product Name	Cyclobutanamine, 2,2-Dimethyl-, Hydrochloride (1:1)
CAS No.	1803562-44-8
Molecular Formula	C6H14ClN
Molecular Weight	135.63 g/mol
Synonyms	2,2-Dimethylcyclobutanamine Hydrochloride; 2,2-Dimethylcyclobutan-1-amine hydrochloride; 1-Cyclobutanamine, 2,2-dimethyl-, hydrochloride; (2,2-Dimethylcyclobutyl)amine hydrochloride; 2,2-Dimethyl-1-aminocyclobutane hydrochloride; 1-Amino-2,2-dimethylcyclobutane hydrochloride
EINECS	Contact for details

Quality Control

Our Cyclobutanamine, 2,2-Dimethyl-, Hydrochloride (1:1) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.