Description

3-(Difluoromethyl)-1-Methyl-1H-Pyrazol-4-Amine is a high-purity, specialized pyrazole derivative building block of significant interest in advanced organic synthesis. This compound is valued for its unique difluoromethylated amine structure, which is crucial for modulating the physicochemical and biological properties of target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition or receptor modulation.
• Agrochemical Synthesis: Used in the research and development of next-generation pesticides, herbicides, and fungicides, where the difluoromethyl group can enhance metabolic stability and bioavailability.
• Chemical Biology Probe Development: Serves as a versatile scaffold for creating molecular probes to study biological pathways and protein functions.
• Material Science Research: Employed in the synthesis of specialized polymers or ligands where the pyrazole core provides specific coordination or binding properties.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	3-(Difluoromethyl)-1-Methyl-1H-Pyrazol-4-Amine
CAS No.	1801762-09-3
Molecular Formula	C5H7F2N3
Molecular Weight	147.13 g/mol
Synonyms	1-Methyl-3-(difluoromethyl)-1H-pyrazol-4-amine; 4-Amino-1-methyl-3-(difluoromethyl)pyrazole; 3-(Difluoromethyl)-1-methyl-4-aminopyrazole; 1-Methyl-3-difluoromethyl-4-aminopyrazole; 4-Amino-3-difluoromethyl-1-methylpyrazole; 1-Methyl-3-(difluoromethyl)-1H-pyrazol-4-ylamine; DFMPA
EINECS	Contact for details

Quality Control

Our 3-(Difluoromethyl)-1-Methyl-1H-Pyrazol-4-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.