Description

2-(Dihydroxyboranyl)-6-Fluorobenzoic Acid is a high-purity boronic acid derivative, a key building block in modern synthetic chemistry. Its value lies in its dual functionality, serving as a versatile intermediate for constructing complex molecules via cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and advanced materials. Its specific structure makes it a critical reagent for Suzuki-Miyaura coupling, enabling the formation of carbon-carbon bonds under mild conditions.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing active pharmaceutical ingredients (APIs), especially in oncology and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific fluorinated aromatic structures.
• Suzuki-Miyaura Cross-Coupling Reagent: Serves as a key organoboron reagent for palladium-catalyzed cross-coupling reactions to form biaryl and other complex aromatic systems.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and organic semiconductors, where fluorinated boronic acids modify electronic properties.
• Chemical Biology & Proteomics: Acts as a handle for bioconjugation and the development of chemical probes and inhibitors targeting specific enzymes or proteins.
• Ligand Synthesis for Catalysis: Used to prepare sophisticated ligands for transition metal catalysts used in asymmetric synthesis and other advanced catalytic processes.

Basic Information

Product Name	2-(Dihydroxyboranyl)-6-Fluorobenzoic Acid
CAS No.	1799979-96-6
Molecular Formula	C7H6BFO4
Molecular Weight	183.93 g/mol
Synonyms	6-Fluoro-2-boronobenzoic Acid; 2-Borono-6-fluorobenzoic Acid; (6-Fluoro-2-carboxyphenyl)boronic Acid; 6-Fluoro-2-carboxyphenylboronic Acid; 2-Carboxy-6-fluorophenylboronic Acid; B-(6-Fluoro-2-carboxyphenyl)boronic Acid; 2-Fluoro-6-boronobenzoic Acid (ambiguous); 1799979-96-6
EINECS	Contact for details

Quality Control

Our 2-(Dihydroxyboranyl)-6-Fluorobenzoic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and commercial synthesis. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. We adhere to cGMP principles where applicable to support our customers' regulatory and quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition. Keep away from incompatible materials such as strong oxidizers.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.