Description

Methyl 2-Carbamoyl-8-Chloroquinoline-4-Carboxylate CAS NO 1799763-11-3 is a high-purity, advanced pharmaceutical intermediate characterized by its quinoline core structure. This compound is of significant value in medicinal chemistry for the synthesis of novel active pharmaceutical ingredients (APIs) and bioactive molecules. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in the fields of oncology and infectious diseases.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially those targeting specific enzymatic pathways.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new quinoline-based therapeutics.
• Anticancer Agent Development: Serves as a precursor for compounds being investigated for their antitumor and antiproliferative properties.
• Antimicrobial Research: Utilized in the development of new agents against bacterial, fungal, or parasitic infections, leveraging the bioactive quinoline scaffold.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.

Basic Information

Product Name	Methyl 2-Carbamoyl-8-Chloroquinoline-4-Carboxylate
CAS No.	1799763-11-3
Molecular Formula	C₁₂H₉ClN₂O₃
Molecular Weight	264.66 g/mol
Synonyms	Methyl 8-chloro-2-carbamoylquinoline-4-carboxylate; 8-Chloro-2-carbamoylquinoline-4-carboxylic acid methyl ester; 4-Quinolinecarboxylic acid, 8-chloro-2-(aminocarbonyl)-, methyl ester; 1799763-11-3; Methyl 2-(aminocarbonyl)-8-chloroquinoline-4-carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 2-Carbamoyl-8-Chloroquinoline-4-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be stored away from direct light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.