Description

(2S,3S,4R)-1-tert-Butyl 2-Methyl 4-((3-(1,1-Difluorobut-3-En-1-Yl)-7-Ethoxyquinoxalin-2-Yl)Oxy)-3-Ethylpyrrolidine-1,2-Dicarboxylate is a sophisticated, high-purity chiral intermediate featuring a complex molecular architecture. This compound is of critical importance in modern pharmaceutical research and development, serving as a key building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is specifically designed for use by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries, where its unique stereochemistry and functional groups enable the construction of targeted therapeutic molecules.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon in the multi-step synthesis of potential drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities with improved efficacy and safety profiles.
• Process Chemistry Development: Serves as a reference standard and starting material for scaling up and optimizing synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Asymmetric Synthesis: Leverages its defined (2S,3S,4R) stereochemistry to induce chirality in downstream reactions, ensuring the production of enantiomerically pure final compounds.
• Contract Research & Manufacturing (CRMO): Supplied to organizations specializing in custom synthesis and development of complex molecules for clinical trials.

Basic Information

Product Name	(2S,3S,4R)-1-tert-Butyl 2-Methyl 4-((3-(1,1-Difluorobut-3-En-1-Yl)-7-Ethoxyquinoxalin-2-Yl)Oxy)-3-Ethylpyrrolidine-1,2-Dicarboxylate
CAS No.	1799733-69-9
Molecular Formula	C30H38F2N2O7
Molecular Weight	576.64 g/mol
Synonyms	1-(1,1-Dimethylethyl) 2-methyl (2S,3S,4R)-4-[[3-(1,1-difluoro-3-buten-1-yl)-7-ethoxy-2-quinoxalinyl]oxy]-3-ethyl-1,2-pyrrolidinedicarboxylate; 1-tert-Butyl 2-methyl (2S,3S,4R)-4-[(3-(1,1-difluorobut-3-en-1-yl)-7-ethoxyquinoxalin-2-yl)oxy]-3-ethylpyrrolidine-1,2-dicarboxylate; BOC-Protected Chiral Pyrrolidine Quinoxaline Derivative; CAS 1799733-69-9; Advanced Pharmaceutical Intermediate 1799733-69-9; Chiral Difluoro Alkenyl Quinoxaline Ester.
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced and analyzed under strict quality management systems. We provide comprehensive Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles, ensuring traceability and compliance with research and development standards. Our quality protocols are designed to support regulatory filings, with testing performed using advanced analytical techniques including HPLC, GC, NMR, and MS.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.