Description

Xphos Pd(Crotyl)Cl is a highly specialized palladium-based catalyst featuring the bulky, electron-rich XPhos ligand. This compound is engineered to deliver exceptional selectivity and activity in challenging cross-coupling reactions, enabling the efficient synthesis of complex organic molecules. It is an indispensable tool for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors, where precise bond formation is critical.

Application

• Cross-Coupling Reactions: A premier catalyst for Buchwald-Hartwig amination, Suzuki-Miyaura, and Negishi cross-couplings, especially with sterically hindered substrates.
• Pharmaceutical Intermediate Synthesis: Enables the construction of key C-N and C-C bonds in the development of active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides requiring selective coupling steps.
• Material Science: Facilitates the creation of conjugated polymers and organic electronic materials through efficient coupling methodologies.
• Process Chemistry & Scale-Up: Valued for its robustness and consistent performance in optimizing synthetic routes from lab to pilot scale.
• Academic & Industrial R&D: A catalyst of choice for methodological development and exploring new chemical space in organic synthesis.

Basic Information

Product Name	Xphos Pd(Crotyl)Cl
CAS No.	1798782-02-1
Molecular Formula	C31H41ClP2Pd
Molecular Weight	625.46 g/mol
Synonyms	Chloro(2-methyl-2-propenyl)[2-dicyclohexylphosphino-2',4',6'-triisopropyl-1,1'-biphenyl]palladium; Palladium, chloro(2-methyl-2-propenyl-KC)[2-[dicyclohexylphosphino]-2',4',6'-triisopropyl[1,1'-biphenyl]-2-yl]-; XPhos Pd Crotyl Chloride; XPhos-Pd(crotyl)Cl; Pd(XPhos)(crotyl)Cl; (2-Methylallyl)palladium(II) chloride XPhos complex
EINECS	Contact for details

Quality Control

Every batch of Xphos Pd(Crotyl)Cl is manufactured and tested under stringent quality management protocols to ensure high catalytic performance and lot-to-lot consistency. Our quality assurance includes comprehensive analytical characterization to verify identity, purity, and activity. Certificates of Analysis (COA) detailing specific test results are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry place. This material is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain catalytic activity.

Specification

Item	Specification
Appearance	Yellow to orange solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Pd Content	Contact for details
Solubility	Soluble in common organic solvents (THF, DCM, toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.