Description

4-Nitro-3-(2,2,2-trifluoro-ethoxy)-1H-pyrazole is a high-purity, functionalized pyrazole derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both nitro and trifluoroethoxy substituents, makes it a valuable intermediate for creating novel compounds with specific electronic and steric properties. This chemical is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in medicinal chemistry programs targeting novel therapeutic agents.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents, including herbicides and fungicides, where its fluorinated moiety can enhance biological activity and stability.
• Material Science Research: Serves as a precursor for synthesizing specialized ligands, polymers, or functional materials that require nitro-aromatic or fluorine-containing components.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological systems and mechanisms.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	4-Nitro-3-(2,2,2-trifluoro-ethoxy)-1H-pyrazole
CAS No.	1795502-95-2
Molecular Formula	C5H4F3N3O3
Molecular Weight	211.10 g/mol
Synonyms	4-Nitro-3-(2,2,2-trifluoroethoxy)-1H-pyrazole; 3-(2,2,2-Trifluoroethoxy)-4-nitro-1H-pyrazole; 1H-Pyrazole, 4-nitro-3-(2,2,2-trifluoroethoxy)-; 4-Nitro-3-(trifluoroethoxy)pyrazole; 4-Nitro-3-(2,2,2-trifluoroethyloxy)pyrazole
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with industry standards. We employ advanced analytical techniques, including HPLC, NMR, and MS, to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.