Description

5-Azaspiro[3.4]Octane Hydrobromide is a high-purity, advanced pharmaceutical intermediate and building block of significant interest in modern organic synthesis. This compound matters for its unique spirocyclic structure, which is a privileged scaffold in medicinal chemistry, offering a three-dimensional framework that can enhance drug-like properties. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, particularly for central nervous system (CNS) targets and other small molecule drug discovery programs. The salt form provides improved stability and handling characteristics for precise formulation work.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs) targeting neurological disorders.
• Medicinal Chemistry Research: Used as a core scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• CNS Drug Development: Employed in the research of potential treatments for conditions such as depression, anxiety, and neurodegenerative diseases.
• Chemical Biology Probes: Serves as a starting material for creating molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic routes.
• Academic Research: A valuable reagent for universities and institutes exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Item	Detail
Product Name	5-Azaspiro[3.4]Octane Hydrobromide
CAS No.	1795283-50-9
Molecular Formula	C7H14N·HBr
Molecular Weight	192.10 g/mol
Synonyms	5-Azaspiro[3.4]octane, hydrobromide; 1-Azaspiro[3.4]octane hydrobromide; Azaspirooctane HBr; Spiro[3.4]octan-5-amine hydrobromide; 5-Aza-spiro[3.4]octane hydrobromide salt; 5-Azaspiro[3.4]octane HBr; 1795283-50-9; CAS 1795283-50-9
EINECS	Contact for details

Quality Control

Our 5-Azaspiro[3.4]Octane Hydrobromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with the standards expected for pharmaceutical R&D, ensuring reliability and consistency for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.