Description

7-Difluoromethyl-2,5-Dimethyl-Pyrazolo[1,5-A]Pyrimidine is a high-value, fluorinated pyrazolopyrimidine derivative, a crucial advanced intermediate in modern synthetic chemistry. Its core value lies in enabling the development of novel active pharmaceutical ingredients (APIs) and agrochemicals by providing a versatile, functionalized heterocyclic scaffold. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate difluoromethylated motifs into new molecular entities.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides where the difluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for functional organic materials, including organic light-emitting diodes (OLEDs) and liquid crystals.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic & Industrial R&D: Fundamental research tool in medicinal and synthetic organic chemistry laboratories for exploring new chemical space.

Basic Information

Product Name	7-Difluoromethyl-2,5-Dimethyl-Pyrazolo[1,5-A]Pyrimidine
CAS No.	1795186-93-4
Molecular Formula	C9H8F2N4
Molecular Weight	210.19 g/mol
Synonyms	7-(Difluoromethyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidine; 2,5-Dimethyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidine; Pyrazolo[1,5-a]pyrimidine, 7-(difluoromethyl)-2,5-dimethyl-; 7-Difluoromethyl-2,5-dimethylpyrazolo[1,5-a]pyrimidine
EINECS	Contact for details

Quality Control

Our 7-Difluoromethyl-2,5-Dimethyl-Pyrazolo[1,5-A]Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.