Description

5-Tosyl-2-Oxa-5-Azabicyclo[2.2.2]Octane is a high-purity, advanced pharmaceutical intermediate featuring a unique bridged bicyclic structure. This compound is of significant value in medicinal chemistry for its role as a versatile building block in the synthesis of complex, biologically active molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new drug candidates, particularly within the fields of central nervous system (CNS) and antiviral therapeutics.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a constrained scaffold to explore structure-activity relationships (SAR) in drug discovery programs.
• Organic Synthesis Building Block: Employed in the construction of complex heterocyclic compounds due to its reactive tosyl and bridged amine functionalities.
• Process Chemistry Development: Serves as a critical intermediate in scaling up synthetic routes for preclinical and clinical trial material.
• Academic Research: Utilized in universities and research institutes for studying new synthetic methodologies and reaction mechanisms.

Basic Information

Product Name	5-Tosyl-2-Oxa-5-Azabicyclo[2.2.2]Octane
CAS No.	1788044-07-4
Molecular Formula	C13H17NO3S
Molecular Weight	267.35 g/mol
Synonyms	2-Oxa-5-azabicyclo[2.2.2]octane, 5-(4-methylbenzenesulfonyl)-; 5-Tosyl-2-oxa-5-azabicyclo[2.2.2]octane; 5-(p-Toluenesulfonyl)-2-oxa-5-azabicyclo[2.2.2]octane; 5-(Tosyl)-2-oxa-5-azabicyclo[2.2.2]octane; 5-Tosyl-2-oxa-5-azabicyclo[2.2.2]oct-3-ene (common misnomer for related structure); Bicyclic Tosyl Amine Ether; 1788044-07-4
EINECS	Contact for details

Quality Control

Our 5-Tosyl-2-Oxa-5-Azabicyclo[2.2.2]Octane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.