Description

3-Quinolinecarboxylic Acid, 1-(6-Amino-3,5-Difluoro-2-Pyridinyl)-6-Fluoro-1,4-Dihydro-7-[3-(2-Methyl-1-Azetidinyl]-4-Oxo-, Ethyl Ester is a sophisticated, high-purity pharmaceutical intermediate designed for advanced synthesis. This compound matters because it provides a critical building block for the development of novel fluoroquinolone antibiotics and other active pharmaceutical ingredients (APIs). It is essential for R&D chemists and process development scientists in the pharmaceutical and biotechnology industries who require reliable, high-quality intermediates for complex synthetic routes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of next-generation fluoroquinolone antibiotic candidates.
• Active Pharmaceutical Ingredient (API) Development: Used in research and process development for novel antibacterial agents.
• Chemical Synthesis Research: Serves as a versatile scaffold for medicinal chemistry and structure-activity relationship (SAR) studies.
• Process Chemistry: Employed in scale-up and optimization of manufacturing routes for complex drug molecules.
• Contract Manufacturing (CMO): Supplied to organizations specializing in the production of advanced pharmaceutical intermediates.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and antibiotic mechanisms.

Basic Information

Product Name	3-Quinolinecarboxylic Acid, 1-(6-Amino-3,5-Difluoro-2-Pyridinyl)-6-Fluoro-1,4-Dihydro-7-[3-(2-Methyl-1-Azetidinyl]-4-Oxo-, Ethyl Ester
CAS No.	1788043-98-0
Molecular Formula	C21H20F3N5O3
Molecular Weight	447.41 g/mol
Synonyms	Ethyl 1-(6-Amino-3,5-difluoropyridin-2-yl)-6-fluoro-7-(3-(2-methylazetidin-1-yl))-4-oxo-1,4-dihydroquinoline-3-carboxylate; 1-(6-Amino-3,5-difluoro-2-pyridinyl)-6-fluoro-1,4-dihydro-7-[3-(2-methyl-1-azetidinyl)]-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester; 1788043-98-0; ABT-492 Intermediate; Zoliflodacin Intermediate; Gepotidacin Intermediate; Novel Fluoroquinolone Intermediate; 3-Quinolinecarboxylic acid ethyl ester derivative
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring consistency and traceability for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; ensure containers are opaque or stored in dark conditions. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Single Maximum Impurity	≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.