Description

tert-Butyl ((1S,3S)-3-Aminocyclohexyl)Carbamate is a high-purity, chiral Boc-protected cyclohexylamine derivative, serving as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring precise stereochemistry and reliable protecting group chemistry for amine functionalities. It is primarily utilized in the pharmaceutical and agrochemical industries for the development of novel active ingredients and complex molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and metabolic disease targets.
• Peptide Synthesis: Used as a protected amino acid analog for introducing constrained cyclohexyl-based structures into peptide chains to modulate biological activity and stability.
• Agrochemical Research: Serves as a precursor in the synthesis of novel herbicides, fungicides, and insecticides that require specific three-dimensional configurations for efficacy.
• Ligand and Catalyst Development: Employed in the creation of chiral ligands and organocatalysts for asymmetric synthesis applications.
• Chemical Biology Probes: Utilized to construct molecular probes for studying enzyme mechanisms and protein-protein interactions.
• Custom Synthesis & Scale-Up: An important starting material for contract research and manufacturing organizations (CROs/CMOs) producing custom fine chemicals at various scales.

Basic Information

Product Name	tert-Butyl ((1S,3S)-3-Aminocyclohexyl)Carbamate
CAS No.	1788036-28-1
Molecular Formula	C11H22N2O2
Molecular Weight	214.31 g/mol
Synonyms	(1S,3S)-3-[(tert-Butoxycarbonyl)amino]cyclohexanamine; (1S,3S)-3-(Boc-amino)cyclohexylamine; tert-Butyl N-[(1S,3S)-3-aminocyclohexyl]carbamate; (1S,3S)-3-Aminocyclohexylcarbamic acid tert-butyl ester; Boc-(1S,3S)-ACHA; (1S,3S)-Boc-DACH; (1S,3S)-3-(tert-Butoxycarbonylamino)cyclohexan-1-amine
EINECS	Contact for details

Quality Control

Our tert-Butyl ((1S,3S)-3-Aminocyclohexyl)Carbamate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and cGMP manufacturing. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.