Description

9-Benzyl-1-Oxa-9-Azaspiro[5.5]Undecan-4-Ol is a sophisticated spirocyclic organic compound featuring a benzyl-substituted oxa-aza heterocyclic core structure. This compound serves as a valuable building block and key intermediate in advanced organic synthesis, particularly for the development of novel pharmacologically active molecules. It is primarily utilized by pharmaceutical R&D organizations, fine chemical manufacturers, and academic research institutions engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic agents.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in drug discovery programs targeting spirocyclic and heterocyclic pharmacophores.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses to introduce the 1-oxa-9-azaspiro[5.5]undecane moiety, a privileged structure in medicinal chemistry.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Academic & Process Chemistry: Used in university and industrial labs for studying novel synthetic methodologies, asymmetric synthesis, and reaction optimization.

Basic Information

Product Name	9-Benzyl-1-Oxa-9-Azaspiro[5.5]Undecan-4-Ol
CAS No.	1785761-76-3
Molecular Formula	C16H23NO2
Molecular Weight	261.36 g/mol
Synonyms	9-Benzyl-1-oxa-9-azaspiro[5.5]undecan-4-ol; 1-Oxa-9-azaspiro[5.5]undecan-4-ol, 9-benzyl-; 9-Benzyl-1-oxa-9-azaspiro[5.5]undecane-4-ol; 4-Hydroxy-9-benzyl-1-oxa-9-azaspiro[5.5]undecane; 9-Benzyl-4-hydroxy-1-oxa-9-azaspiro[5.5]undecane; Benzyl-spiro-oxa-aza-undecanol; Bz-OAU-OH (abbrev.); Spirocyclic benzyl amino alcohol intermediate.
EINECS	Contact for details

Quality Control

Our 9-Benzyl-1-Oxa-9-Azaspiro[5.5]Undecan-4-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring suitability for use in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.