Description

Phenol, 5-Chloro-2-Fluoro-3-Methoxy- is a high-purity, multi-functional aromatic building block designed for advanced synthetic chemistry. This compound matters as a critical intermediate for constructing complex molecules, offering precise substitution patterns for regioselective reactions. Pharmaceutical, agrochemical, and advanced material researchers need it for developing new active ingredients and functional polymers. Its unique halogen and methoxy substitution provides versatile reactivity for cross-coupling and further functionalization.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the chloro-fluoro-methoxy motif imparts specific biological activity.
• Liquid Crystal & OLED Material Precursor: Serves as a core structure in the development of specialty chemicals for electronic displays and organic light-emitting diodes.
• Polymer & Resin Modifier: Incorporated into polymer chains to alter physical properties such as thermal stability, solubility, and refractive index.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions due to its halogen substituents.
• Chemical Research & Development: A versatile reagent for medicinal chemistry and material science research in academic and industrial laboratories.

Basic Information

Product Name	Phenol, 5-Chloro-2-Fluoro-3-Methoxy-
CAS No.	1785505-25-0
Molecular Formula	C7H6ClFO2
Molecular Weight	176.57 g/mol
Synonyms	5-Chloro-2-fluoro-3-methoxyphenol; 3-Methoxy-5-chloro-2-fluorophenol; 2-Fluoro-5-chloro-3-methoxyphenol; 5-Chloro-2-fluoro-3-hydroxyanisole; 2-Fluoro-5-chloro-3-methoxyphenol; 5-Chloro-2-fluoro-3-methoxyphenol (primary IUPAC); Phenol, 5-chloro-2-fluoro-3-methoxy- (CAS index name)
EINECS	Contact for details

Quality Control

Our Phenol, 5-Chloro-2-Fluoro-3-Methoxy- is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP and research use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorinating agents. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.