Description

tert-Butyl 1-Amino-3-Azabicyclo[3.1.1]heptane-3-carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a unique, rigid bicyclic scaffold. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on developing new therapeutic agents, particularly in areas such as central nervous system (CNS) and metabolic disease research.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, especially those targeting G-protein-coupled receptors (GPCRs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its constrained, three-dimensional structure.
• API Development: Serves as a core scaffold in the development of potential therapeutics for neurological disorders and psychiatric conditions.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target validation.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.

Basic Information

Product Name	tert-Butyl 1-Amino-3-Azabicyclo[3.1.1]heptane-3-carboxylate
CAS No.	1784306-64-4
Molecular Formula	C11H20N2O2
Molecular Weight	212.29 g/mol
Synonyms	1-Amino-3-azabicyclo[3.1.1]heptane-3-carboxylic acid tert-butyl ester; 3-Boc-1-amino-3-azabicyclo[3.1.1]heptane; tert-Butyl 1-amino-3-azabicyclo[3.1.1]heptane-3-carboxylate; 1-Amino-3-azabicyclo[3.1.1]heptane-3-carboxylic acid 1,1-dimethylethyl ester; 3-Azabicyclo[3.1.1]heptane-3-carboxylic acid, 1-amino-, 1,1-dimethylethyl ester; 1-Amino-3-(tert-butoxycarbonyl)-3-azabicyclo[3.1.1]heptane
EINECS	Contact for details

Quality Control

Our tert-Butyl 1-Amino-3-Azabicyclo[3.1.1]heptane-3-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to support your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.