Description

tert-Butyl 1-(Aminomethyl)-5-Azaspiro[2.5]Octane-5-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is valued for its role as a critical building block in the synthesis of novel, complex active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within the fields of central nervous system (CNS) and metabolic disease research.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates.
• Proteolysis Targeting Chimera (PROTAC) Development: Used as a component in the linker or warhead sections of bifunctional molecules designed for targeted protein degradation.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing libraries of compounds for high-throughput screening and structure-activity relationship (SAR) studies.
• Synthesis of Bioactive Molecules: Employed in the construction of complex molecules targeting G-protein-coupled receptors (GPCRs) and other biological targets.
• Chemical Biology Tool Development: Utilized in the creation of probes and ligands for studying enzyme function and cellular pathways.

Basic Information

Product Name	tert-Butyl 1-(Aminomethyl)-5-Azaspiro[2.5]Octane-5-Carboxylate
CAS No.	1782580-90-8
Molecular Formula	C13H24N2O2
Molecular Weight	240.34 g/mol
Synonyms	5-Azaspiro[2.5]octane-5-carboxylic acid, 1-(aminomethyl)-, 1,1-dimethylethyl ester; 1,1-Dimethylethyl 1-(aminomethyl)-5-azaspiro[2.5]octane-5-carboxylate; tert-Butyl 1-(aminomethyl)-5-azaspiro[2.5]octane-5-carboxylate; 1-(Aminomethyl)-5-azaspiro[2.5]octane-5-carboxylic acid tert-butyl ester; Boc-protected 1-(aminomethyl)-5-azaspiro[2.5]octane; CAS 1782580-90-8
EINECS	Contact for details

Quality Control

Our production of tert-Butyl 1-(Aminomethyl)-5-Azaspiro[2.5]Octane-5-Carboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials are characterized and released against comprehensive specifications, supported by analytical data from techniques including HPLC, NMR, and MS. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere to maintain stability and purity. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.