Description

3-(2-Iodoethyl)Oxetane is a specialized oxetane derivative functionalized with an iodoethyl side chain, serving as a valuable bifunctional building block in advanced organic synthesis. This compound is particularly significant for its dual reactivity, where the oxetane ring can undergo controlled ring-opening polymerization or serve as a protected alcohol equivalent, while the iodoethyl moiety provides a versatile handle for further functionalization via cross-coupling reactions. It is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for developing novel active ingredients, polymers, and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting complex molecular architectures.
• Polymer Science: Monomer for the synthesis of functional polyethers and advanced polymeric materials with tailored properties via cationic ring-opening polymerization (CROP).
• Agrochemical Synthesis: Intermediate in the development of new herbicides, fungicides, and plant growth regulators requiring specific heterocyclic frameworks.
• Ligand and Catalyst Development: Precursor for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis and transition metal catalysis.
• Material Functionalization: Used to introduce reactive sites onto surfaces or polymer backbones for creating smart materials and coatings.
• Cross-Coupling Reactions: Serves as an alkyl halide coupling partner in palladium-catalyzed reactions (e.g., Negishi, Suzuki-Miyaura) for carbon-carbon bond formation.

Basic Information

Product Name	3-(2-Iodoethyl)Oxetane
CAS No.	1782577-96-1
Molecular Formula	C5H9IO
Molecular Weight	212.03 g/mol
Synonyms	2-(2-Iodoethyl)oxetane; Oxetane, 3-(2-iodoethyl)-; 3-(2-Iodoethyl)-1-oxacyclobutane; 2-Iodoethyloxetane; 3-Iodoethyloxetane; Iodoethyl oxetane; Oxetanyl ethyl iodide
EINECS	Contact for details

Quality Control

Our 3-(2-Iodoethyl)Oxetane is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatographic purity assessment and structural confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. Keep the container in a cool, dry, and well-ventilated place, away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.