Description

3-Furancarboxylic Acid, 4,4-Difluorotetrahydro-3-Methyl- is a high-purity fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its unique structural features, combining a furan carboxylic acid core with strategic fluorine substitution, which is critical for modulating the physicochemical and metabolic properties of target molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting improved bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluorine atoms can enhance biological activity and environmental persistence.
• Material Science Research: Serves as a specialized monomer or precursor for developing novel fluorinated polymers with unique surface properties and chemical resistance.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create sophisticated ligands for catalytic systems.
• Chemical Biology Probes: Useful for synthesizing labeled compounds or probes to study biological mechanisms and pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring fluorinated heterocycles.

Basic Information

Product Name	3-Furancarboxylic Acid, 4,4-Difluorotetrahydro-3-Methyl-
CAS No.	1782346-79-5
Molecular Formula	C7H8F2O3
Molecular Weight	178.14 g/mol
Synonyms	4,4-Difluoro-3-methyltetrahydrofuran-3-carboxylic Acid; 3-Methyl-4,4-difluorotetrahydrofuran-3-carboxylic Acid; 4,4-Difluoro-3-methyltetrahydro-3-furancarboxylic Acid; 3-Carboxy-3-methyl-4,4-difluorotetrahydrofuran; 1782346-79-5; 4,4-Difluoro-3-methyloxolane-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Furancarboxylic Acid, 4,4-Difluorotetrahydro-3-Methyl- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed batch-specific results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorinating agents. The container must be kept tightly closed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.