Description

3-Chloro-6-Fluoro-2-Methoxybenzoic Acid is a high-purity, multi-functional benzoic acid derivative distinguished by its specific halogen and methoxy substitution pattern. This compound is a critical synthetic intermediate valued for its role in constructing complex molecular architectures, particularly in advanced pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for synthesizing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated aromatic structure.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and polymers where specific electronic properties are required.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences industry.
• Academic and Institutional Research: Utilized in university and government labs for methodological studies in organic synthesis and medicinal chemistry.

Basic Information

Product Name	3-Chloro-6-Fluoro-2-Methoxybenzoic Acid
CAS No.	1781848-13-2
Molecular Formula	C8H6ClFO3
Molecular Weight	204.58 g/mol
Synonyms	2-Methoxy-3-chloro-6-fluorobenzoic Acid; 3-Chloro-6-fluoro-2-methoxybenzoic acid; 6-Fluoro-3-chloro-2-methoxybenzoic Acid; Benzoic acid, 3-chloro-6-fluoro-2-methoxy-; 1781848-13-2; 3-Chloro-6-fluoro-o-anisic acid
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-6-Fluoro-2-Methoxybenzoic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for research and scale-up applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments. Our standard quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (HPLC, Area %)	≥98.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.