Description

.Alpha.-Pyrrolidinopentiophenone-D8 (Hydrochloride) is a deuterated analog of a pyrrolidinophenone compound, serving as a high-purity internal standard and reference material. Its core value lies in enabling precise quantitative analysis and method validation in complex matrices, ensuring data accuracy and regulatory compliance. This compound is essential for analytical chemists and researchers in forensic toxicology, pharmaceutical development, and clinical research laboratories who require reliable isotopic-labeled standards for mass spectrometry.

Application

• Internal Standard for LC-MS/MS: Primary use as a quantitative reference standard in liquid chromatography-tandem mass spectrometry for forensic and clinical analysis.
• Metabolite Studies: Used in pharmaceutical R&D for tracking and quantifying drug metabolites in pharmacokinetic and metabolic stability studies.
• Forensic Toxicology: Critical for the accurate identification and quantification of target analytes in biological samples for legal and medical purposes.
• Method Development & Validation: Employed to develop, optimize, and validate analytical methods, ensuring specificity, accuracy, and precision.
• Quality Control in Reference Material Production: Serves as a key component in manufacturing certified reference materials (CRMs) for laboratory proficiency testing.
• Isotope Dilution Mass Spectrometry (IDMS): Applied in high-accuracy measurement techniques where the deuterated compound is used to correct for analyte loss during sample preparation.

Basic Information

Product Name	.Alpha.-Pyrrolidinopentiophenone-D8 (Hydrochloride)
CAS No.	1781744-06-6
Molecular Formula	C15H14D8ClNO
Molecular Weight	Contact for details
Synonyms	α-Pyrrolidinopentiophenone-D8 hydrochloride
α-PVP-D8 hydrochloride
1-Phenyl-2-(pyrrolidin-1-yl)-1-pentanone-D8 hydrochloride
Pyrrolidinopentiophenone-D8 HCl
Deuterated α-PVP hydrochloride
α-Pyrrolidinovalerophenone-D8 hydrochloride
Deuterium-labeled α-PVP HCl (8 deuterium atoms)
EINECS	Contact for details

Quality Control

Our .Alpha.-Pyrrolidinopentiophenone-D8 (Hydrochloride) is manufactured under strict quality systems to ensure the high purity and isotopic enrichment required for analytical applications. Each batch is characterized using advanced techniques including NMR, HPLC, and mass spectrometry to confirm chemical identity, isotopic purity (>98 atom % D), and chemical purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability. For long-term storage, consider desiccant in the container.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.