Description

1-(3-Chloro-2-Fluoro-6-Methoxy-Phenyl)-Ethanone is a high-purity fluorinated aromatic ketone building block of significant importance in advanced organic synthesis. This compound is valued for its unique substitution pattern, which makes it a versatile intermediate for constructing complex molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine and chlorine substituents enhance biological activity.
• Material Science Research: Serves as a precursor for the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: Employed in academic and industrial labs for methodological studies, catalysis research, and the creation of novel chemical libraries.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke fine chemicals for clients.

Basic Information

Product Name	1-(3-Chloro-2-Fluoro-6-Methoxy-Phenyl)-Ethanone
CAS No.	1781675-28-2
Molecular Formula	C9H8ClFO2
Molecular Weight	202.61 g/mol
Synonyms	3'-Chloro-2'-fluoro-6'-methoxyacetophenone; 1-(3-Chloro-2-fluoro-6-methoxyphenyl)ethan-1-one; 2-Fluoro-3-chloro-6-methoxyacetophenone; 3-Chloro-2-fluoro-6-methoxyacetophenone; Acetophenone, 3-chloro-2-fluoro-6-methoxy-; 1-Acetyl-3-chloro-2-fluoro-6-methoxybenzene; 1781675-28-2
EINECS	Contact for details

Quality Control

Our production of 1-(3-Chloro-2-Fluoro-6-Methoxy-Phenyl)-Ethanone adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR spectroscopy. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.