Description

3-Cyclobutylpicolinic Acid is a high-purity organic building block of significant interest in advanced chemical synthesis. This compound serves as a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique cyclobutyl-picolinic acid scaffold enables precise molecular design. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for lead optimization and process development.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition.
• Agrochemical Synthesis: Used as a building block for creating novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand Precursor: Serves as a starting material for the synthesis of complex ligands used in catalysis and material science.
• Chemical Research: Employed in academic and industrial R&D for exploring new chemical entities and reaction pathways.
• Custom Synthesis: A foundational component for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis for clients.

Basic Information

Product Name	3-Cyclobutylpicolinic Acid
CAS No.	1781644-15-2
Molecular Formula	C10H11NO2
Molecular Weight	177.20 g/mol
Synonyms	3-Cyclobutylpyridine-2-carboxylic Acid; 2-Pyridinecarboxylic Acid, 3-Cyclobutyl-; Picolinic Acid, 3-Cyclobutyl-; 3-Cyclobutyl-2-pyridinecarboxylic Acid; 3-Cyclobutylpicolinate; 1781644-15-2; Cyclobutylpicolinic Acid
EINECS	Contact for details

Quality Control

Our 3-Cyclobutylpicolinic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are provided and available upon request to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.