Description

2-Bromoquinoline-6-Carboxylic Acid is a high-purity, multi-functional brominated quinoline derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a reactive halogen site and a carboxylic acid functional group on a privileged quinoline scaffold, enabling the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality intermediates for drug discovery and specialty chemical production.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting neurological disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the quinoline core.
• Ligand & Catalyst Synthesis: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science: Employed in the research and development of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology Probes: Utilized to develop fluorescent tags and molecular probes for studying biological processes and diagnostics.
• Custom Synthesis & Contract Manufacturing: A vital building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-Bromoquinoline-6-Carboxylic Acid
CAS No.	1781044-00-5
Molecular Formula	C₁₀H₆BrNO₂
Molecular Weight	252.07 g/mol
Synonyms	6-Carboxy-2-bromoquinoline; 2-Bromo-6-quinolinecarboxylic acid; Quinoline-6-carboxylic acid, 2-bromo-; 2-Bromoquinoline-6-carboxylate; 2-Br-6-COOH-Quinoline
EINECS	Contact for details

Quality Control

Our 2-Bromoquinoline-6-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to cGMP principles and adherence to ISO standards ensure a reliable supply of material suitable for demanding research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.