Description

6-Trifluoromethyl-[1,5]Naphthyridin-4-Ol CAS NO 1777862-42-6 is a high-purity, heterocyclic organic compound featuring a naphthyridine core substituted with a trifluoromethyl group and a hydroxyl moiety. This specific molecular architecture makes it a valuable and versatile building block for advanced chemical synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in drug discovery and agrochemical innovation.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly for targeted therapies.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, leveraging the biological activity of the naphthyridine scaffold.
• Material Science Research: Serves as a building block for developing novel organic electronic materials or metal-organic frameworks (MOFs).
• Ligand and Catalyst Development: The structure can be functionalized to create chelating ligands for catalysis or metal complexation studies.
• Biochemical Probe Synthesis: Utilized in medicinal chemistry to create molecular probes for studying biological pathways and enzyme inhibition.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	6-Trifluoromethyl-[1,5]Naphthyridin-4-Ol
CAS No.	1777862-42-6
Molecular Formula	C9H5F3N2O
Molecular Weight	214.15 g/mol
Synonyms	4-Hydroxy-6-(trifluoromethyl)-1,5-naphthyridine; 6-(Trifluoromethyl)-1,5-naphthyridin-4-ol; 4-Hydroxy-6-trifluoromethyl-1,5-naphthyridine; 1,5-Naphthyridin-4-ol, 6-(trifluoromethyl)-; 6-Trifluoromethyl-1,5-naphthyridin-4-ol; 6-Trifluoromethyl-1,5-naphthyridin-4(1H)-one (tautomer); TFN-OH (abbreviation)
EINECS	Contact for details

Quality Control

Our 6-Trifluoromethyl-[1,5]Naphthyridin-4-Ol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as assay purity and impurity profiles. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP-compliant synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.