Description

1-(Quinazolin-4-Yl)Azetidin-3-Amine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a defined molecular structure. This compound is critical for medicinal chemistry research and development, serving as a key building block in the synthesis of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new drug candidates, particularly in oncology and other targeted therapy areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates, particularly kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes during drug discovery.
• Chemical Biology Probes: Serves as a scaffold for developing tool compounds to study specific biological pathways and target validation.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for the custom production of complex molecules for clients.
• Library Synthesis: Used to generate focused chemical libraries for high-throughput screening against novel biological targets.

Basic Information

Product Name	1-(Quinazolin-4-Yl)Azetidin-3-Amine Hydrochloride
CAS No.	1713160-84-9
Molecular Formula	C11H13N4·HCl
Molecular Weight	236.71 g/mol
Synonyms	1-(4-Quinazolinyl)-3-azetidinamine hydrochloride; 3-Amino-1-(quinazolin-4-yl)azetidine hydrochloride; Azetidin-3-amine, 1-(4-quinazolinyl)-, hydrochloride; 1-(Quinazolin-4-yl)azetidin-3-amine HCl; 4-(3-Aminoazetidin-1-yl)quinazoline hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(Quinazolin-4-Yl)Azetidin-3-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and current industry standards for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.