Description

(E)-3-(4-(Bromomethyl)Phenyl)Acrylic Acid CAS NO 1708953-95-0 is a high-purity, functionalized acrylic acid derivative featuring a bromomethyl group on the phenyl ring, making it a versatile building block for advanced organic synthesis. This compound is valued for its dual reactivity, offering both an acrylic acid moiety for polymerization or Michael addition and a bromomethyl group for nucleophilic substitution or cross-coupling reactions. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for constructing complex molecular scaffolds, as well as by material scientists for creating functional polymers and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in the synthesis of kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators requiring specific aromatic and acrylic functionalities.
• Polymer & Material Science: Serves as a functional monomer or cross-linking agent for synthesizing specialty polymers, liquid crystals, and photo-responsive materials.
• Chemical Biology & Proteomics: Employed as a linker or tagging reagent for bioconjugation strategies, enabling the study of protein interactions and cellular processes.
• Organic Synthesis Building Block: Utilized in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) and as a precursor for more complex heterocyclic and macrocyclic compounds.

Basic Information

Product Name	(E)-3-(4-(Bromomethyl)Phenyl)Acrylic Acid
CAS No.	1708953-95-0
Molecular Formula	C10H9BrO2
Molecular Weight	241.08 g/mol
Synonyms	(E)-3-[4-(Bromomethyl)phenyl]-2-propenoic acid; trans-3-(4-(Bromomethyl)phenyl)acrylic acid; 4-(Bromomethyl)cinnamic acid; (E)-4-(Bromomethyl)cinnamic acid; 2-Propenoic acid, 3-[4-(bromomethyl)phenyl]-, (2E)-; p-(Bromomethyl)cinnamic acid; BCPCA; 1708953-95-0
EINECS	Contact for details

Quality Control

Our (E)-3-(4-(Bromomethyl)Phenyl)Acrylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.