Description

2-[4-(3-Bromophenyl)-1-(tert-Butoxycarbonyl)Piperidin-4-Yl]Acetic Acid is a high-purity, advanced pharmaceutical intermediate featuring a piperidine core with a bromophenyl substituent and a protected carboxylic acid group. This compound matters as a critical building block for medicinal chemists, enabling the synthesis of complex molecules with potential therapeutic applications. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, especially those targeting neurological disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for the discovery of new bioactive molecules.
• API Development: Serves as a crucial scaffold in the development of Active Pharmaceutical Ingredients (APIs) for preclinical and clinical trials.
• Chemical Synthesis: Employed in organic synthesis to introduce the 4-(3-bromophenyl)piperidin-4-yl acetic acid moiety into more complex molecular architectures.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.

Basic Information

Product Name	2-[4-(3-Bromophenyl)-1-(tert-Butoxycarbonyl)Piperidin-4-Yl]Acetic Acid
CAS No.	1707358-59-5
Molecular Formula	C18H24BrNO4
Molecular Weight	398.29 g/mol
Synonyms	1-Boc-4-(3-bromophenyl)-4-(carboxymethyl)piperidine; 4-(3-Bromophenyl)-1-[(2-methylpropan-2-yl)oxycarbonyl]piperidine-4-acetic acid; 1-(tert-Butoxycarbonyl)-4-(3-bromophenyl)-4-(carboxymethyl)piperidine; 4-(3-Bromophenyl)-1-Boc-piperidine-4-acetic acid; 2-[1-(tert-Butoxycarbonyl)-4-(3-bromophenyl)piperidin-4-yl]acetic acid; 4-(3-Bromophenyl)-4-(carboxymethyl)piperidine-1-carboxylic acid tert-butyl ester; 1-Boc-4-(3-bromophenyl)-4-piperidineacetic acid
EINECS	Contact for details

Quality Control

Our 2-[4-(4-(3-Bromophenyl)-1-(tert-Butoxycarbonyl)Piperidin-4-Yl]Acetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with the standards expected for pharmaceutical R&D, and we can support custom purity requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.