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(R)-3,3'-Bis(3,5-Dichlorophenyl)-[1,1'-Binapthalene]-2,2'-Diol CAS NO 1706459-29-1


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CAS No.:1706459-29-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(R)-3,3'-Bis(3,5-Dichlorophenyl)-[1,1'-Binapthalene]-2,2'-Diol is a high-value, chiral binaphthol derivative, recognized for its role as a sophisticated ligand and catalyst precursor in asymmetric synthesis. Its precise stereochemistry and unique steric and electronic properties make it indispensable for creating enantiomerically pure compounds, which are critical in advanced pharmaceutical and fine chemical manufacturing. This compound is primarily sought by research institutions and industrial R&D departments focused on developing novel synthetic pathways for active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

  • Asymmetric Catalysis: Serves as a privileged chiral ligand for transition metal-catalyzed reactions, including asymmetric hydrogenation, C-C bond formation, and oxidation.
  • Pharmaceutical Intermediate Synthesis: A key building block in the research and development of enantiomerically pure drug candidates and complex molecules.
  • Material Science Research: Used in the development of chiral polymers, liquid crystals, and other advanced functional materials with specific optical properties.
  • Agrochemical Development: Employed in the synthesis of chiral pesticides and herbicides to enhance efficacy and reduce environmental impact.
  • Academic & Industrial R&D: A vital tool for chemists in exploring new methodologies in stereoselective synthesis and organocatalysis.

Basic Information

Item Details
Product Name (R)-3,3'-Bis(3,5-Dichlorophenyl)-[1,1'-Binapthalene]-2,2'-Diol
CAS No. 1706459-29-1
Molecular Formula C32H18Cl4O2
Molecular Weight 584.30 g/mol
Synonyms (R)-3,3'-Bis(3,5-dichlorophenyl)-1,1'-bi-2-naphthol; (R)-3,3'-Bis(3,5-dichlorophenyl)-BINOL; (R)-3,3'-Bis(3,5-dichlorophenyl)-2,2'-dihydroxy-1,1'-binaphthyl; (R)-3,3'-Di(3,5-dichlorophenyl)-BINOL; (R)-3,3'-Bis(3,5-dichlorophenyl)-H8-BINOL (if hydrogenated); Chiral BINOL Derivative; Asymmetric Catalyst Ligand
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Quality Control

Our (R)-3,3'-Bis(3,5-Dichlorophenyl)-[1,1'-Binapthalene]-2,2'-Diol is produced under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. We employ advanced analytical techniques, including chiral HPLC and NMR spectroscopy, to verify identity and purity. Certificates of Analysis (COA) detailing specific test results are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term storage to prevent potential oxidation. Keep away from strong acids/bases and oxidizing agents.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Enantiomeric Excess (Chiral HPLC) ≥ 99.0% ee
Loss on Drying ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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