Description

2-Methyl-2-Propanyl 5-Bromo-3,4-Dihydro-1(2H)-Quinolinecarboxylate is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active molecules. This compound is critical for research and development in medicinal chemistry, offering a versatile building block for constructing novel heterocyclic scaffolds. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in the areas of central nervous system (CNS) and oncology drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, especially those targeting neurological disorders.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Fine Chemical Synthesis: Used in the production of complex, high-value specialty chemicals and other advanced intermediates.
• Academic & Institutional R&D: Employed in university and research institute laboratories for investigating new synthetic methodologies and heterocyclic chemistry.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing outsourced research and custom synthesis services for the pharmaceutical industry.

Basic Information

Product Name	2-Methyl-2-Propanyl 5-Bromo-3,4-Dihydro-1(2H)-Quinolinecarboxylate
CAS No.	1706449-47-9
Molecular Formula	C14H16BrNO2
Molecular Weight	310.19 g/mol
Synonyms	tert-Butyl 5-bromo-3,4-dihydro-1(2H)-quinolinecarboxylate; 5-Bromo-1,2,3,4-tetrahydroquinoline-1-carboxylic acid tert-butyl ester; 5-Bromo-3,4-dihydro-2H-quinoline-1-carboxylic acid tert-butyl ester; tert-Butyl 5-bromo-1,2,3,4-tetrahydroquinoline-1-carboxylate; 5-Bromo-N-Boc-1,2,3,4-tetrahydroquinoline; 5-Bromo-1-N-Boc-tetrahydroquinoline; 5-Bromo-1-(tert-butoxycarbonyl)-1,2,3,4-tetrahydroquinoline
EINECS	Contact for details

Quality Control

Every batch of 2-Methyl-2-Propanyl 5-Bromo-3,4-Dihydro-1(2H)-Quinolinecarboxylate is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our products are developed to meet the stringent requirements of pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.