Description

2-Amino-Spiro[3.4]Octane-2-Carboxylic Acid is a specialized, high-value spirocyclic amino acid derivative. This compound is a critical building block in modern pharmaceutical research and development, offering a unique three-dimensional scaffold for drug design. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries for the synthesis of novel active pharmaceutical ingredients (APIs) and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates targeting central nervous system (CNS) disorders, metabolic diseases, and other therapeutic areas.
• Peptidomimetics & Constrained Peptides: Used to introduce conformational rigidity into peptide backbones, enhancing metabolic stability and biological activity.
• Chemical Biology Probes: Serves as a building block for creating tool compounds and probes to study enzyme function and protein-protein interactions.
• Asymmetric Synthesis: Acts as a chiral auxiliary or starting material in stereoselective synthesis to create enantiomerically pure compounds.
• Agrochemical Research: Potential intermediate in the development of new, high-performance crop protection agents with novel modes of action.
• Material Science: Research component for developing novel polymers or organic frameworks with specific structural properties.

Basic Information

Product Name	2-Amino-Spiro[3.4]Octane-2-Carboxylic Acid
CAS No.	1706443-01-7
Molecular Formula	C9H15NO2
Molecular Weight	169.22 g/mol
Synonyms	2-Azaspiro[3.4]octane-2-carboxylic acid, 2-amino-; 2-Amino-2-carboxyspiro[3.4]octane; 2-Amino-spiro[3.4]octane-2-carboxylic acid; 2-Azaspiro[3.4]octane-2-carboxylic acid, amino-; 2-Amino-2-azaspiro[3.4]octane-2-carboxylic acid; (2-Amino-2-azaspiro[3.4]oct-2-yl)carboxylic acid; Spirocyclic β-amino acid derivative
EINECS	Contact for details

Quality Control

Our 2-Amino-Spiro[3.4]Octane-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via NMR and MS, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. For long-term storage, consider storing at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.