Description

3,3-Dimethyl-2-Oxa-7-Azaspiro[4.4]Nonane is a sophisticated spirocyclic compound featuring both oxa (oxygen) and aza (nitrogen) heterocycles, serving as a high-value advanced pharmaceutical intermediate and a versatile building block in organic synthesis. Its unique constrained spirocyclic scaffold is crucial for modulating the physicochemical and biological properties of target molecules, making it indispensable for medicinal chemistry research and development. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients with improved metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Medicinal Chemistry Scaffold: Used to introduce conformational rigidity and explore structure-activity relationships (SAR) in lead optimization programs.
• Agrochemical Synthesis: Serves as a precursor for developing new generation pesticides and herbicides with spirocyclic motifs.
• Ligand and Catalyst Development: The nitrogen atom provides a coordination site for creating novel ligands in asymmetric catalysis.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific thermal or mechanical properties.
• Academic & Industrial R&D: A valuable reagent for methodological studies in heterocyclic and spirocyclic chemistry.

Basic Information

Product Name	3,3-Dimethyl-2-Oxa-7-Azaspiro[4.4]Nonane
CAS No.	1706435-18-8
Molecular Formula	C9H17NO
Molecular Weight	155.24 g/mol
Synonyms	2-Oxa-7-azaspiro[4.4]nonane, 3,3-dimethyl-; 3,3-Dimethyl-2-oxa-7-azaspiro[4.4]nonane; 7-Aza-2-oxaspiro[4.4]nonane, 3,3-dimethyl-; Spiro[4.4]nonane, 2-oxa-7-aza-3,3-dimethyl-; 3,3-Dimethyl-2-oxa-7-azaspiro[4.4]nonane (CAS 1706435-18-8)
EINECS	Contact for details

Quality Control

Our 3,3-Dimethyl-2-Oxa-7-Azaspiro[4.4]Nonane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH Q7 guidelines for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.