Description

2-Amino-Spiro[3.5]Nonane-2-Carboxylic Acid is a high-purity, non-proteinogenic amino acid derivative featuring a unique spirocyclic structure. This compound is a critical chiral building block in advanced pharmaceutical research and development, offering a constrained, three-dimensional scaffold for drug design. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries for the synthesis of novel therapeutic candidates, particularly in areas targeting the central nervous system and metabolic diseases.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs) and investigational new drugs.
• Peptidomimetics & Constrained Peptides: Used to introduce conformational rigidity into peptide backbones, enhancing metabolic stability and receptor selectivity.
• Chemical Biology Probes: Serves as a specialized building block for creating tool compounds and probes to study enzyme mechanisms and protein-protein interactions.
• Asymmetric Synthesis: Employed as a chiral auxiliary or precursor in stereoselective catalytic reactions.
• Material Science Research: Potential monomer for the development of novel polymers with specific structural properties.
• Academic & Contract Research: Essential for research institutions and CROs (Contract Research Organizations) engaged in cutting-edge organic and medicinal chemistry projects.

Basic Information

Product Name	2-Amino-Spiro[3.5]Nonane-2-Carboxylic Acid
CAS No.	1706434-87-8
Molecular Formula	C10H17NO2
Molecular Weight	183.25 g/mol
Synonyms	2-Azaspiro[3.5]nonane-2-carboxylic acid, 2-amino-; 2-Amino-2-carboxyspiro[3.5]nonane; 2-Amino-spiro[3.5]nonane-2-carboxylic acid; (2-Amino-2-carboxyethyl)cyclohexane; Spirocyclic β-amino acid; Non-proteinogenic spiro amino acid; 2-Amino-2-spiro[3.5]nonanecarboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Amino-Spiro[3.5]Nonane-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) providing results for assay, chiral purity, and related substances is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.