Description

3,4-Dichloro-5-(Trifluoromethoxy)Phenylaceticacid is a high-purity, advanced pharmaceutical intermediate characterized by its unique halogenated aromatic structure. This compound matters for its critical role as a versatile building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring potent and selective molecular scaffolds. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel Active Pharmaceutical Ingredients (APIs), especially in anti-inflammatory, antiviral, and CNS-targeted drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides and pesticides, leveraging its halogenated structure for enhanced biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of specialty polymers and advanced organic electronic materials due to its electron-withdrawing substituents.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic and Industrial R&D: Fundamental research reagent in medicinal chemistry and chemical biology for probing structure-activity relationships (SAR).

Basic Information

Item	Details
Product Name	3,4-Dichloro-5-(Trifluoromethoxy)Phenylaceticacid
CAS No.	1706430-35-4
Molecular Formula	C9H5Cl2F3O3
Molecular Weight	289.04 g/mol
Synonyms	[3,4-Dichloro-5-(trifluoromethoxy)phenyl]acetic acid; 2-[3,4-Dichloro-5-(trifluoromethoxy)phenyl]acetic acid; 3,4-Dichloro-5-(trifluoromethoxy)benzeneacetic acid; (3,4-Dichloro-5-(trifluoromethoxy)phenyl)acetic acid; CAS 1706430-35-4; 3,4-Dichloro-5-(trifluoromethoxy)phenylacetic acid; 2-(3,4-Dichloro-5-(trifluoromethoxyphenyl)acetic acid
EINECS	Contact for details

Quality Control

Our 3,4-Dichloro-5-(Trifluoromethoxy)Phenylaceticacid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent lot-to-lot quality suitable for sensitive R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under dry, inert conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.