Description

2-(Benzyloxy)-1-Bromo-4-(Trifluoromethoxy)Benzene is a high-purity, advanced organic intermediate featuring a unique trifluoromethoxy and benzyl-protected phenol structure. This compound is valued for its role as a critical building block in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on new active ingredients, where its specific halogen and ether functionalities enable precise structural modifications.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, especially those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the preparation of advanced herbicides and pesticides, where the trifluoromethoxy group can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials and liquid crystals, leveraging its aromatic and halogenated structure.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific, multi-step synthetic routes.

Basic Information

Product Name	2-(Benzyloxy)-1-Bromo-4-(Trifluoromethoxy)Benzene
CAS No.	1704065-45-1
Molecular Formula	C15H12BrF3O2
Molecular Weight	361.16 g/mol
Synonyms	1-Bromo-2-(benzyloxy)-4-(trifluoromethoxy)benzene; 2-Benzyloxy-1-bromo-4-trifluoromethoxybenzene; 4-(Benzyloxy)-3-bromophenyl trifluoromethyl ether; 3-Bromo-4-(benzyloxy)phenyl trifluoromethyl ether; 1-Bromo-4-(trifluoromethoxy)-2-(phenylmethoxy)benzene; Benzene, 1-bromo-2-(benzyloxy)-4-(trifluoromethoxy)-; (3-Bromo-4-(benzyloxy)phenyl)(trifluoromethyl) ether
EINECS	Contact for details

Quality Control

Every batch of 2-(Benzyloxy)-1-Bromo-4-(Trifluoromethoxy)Benzene is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for sensitive R&D and scale-up processes. Certificates of Analysis (COA) with full analytical data are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (HPLC/GC-MS)	Conforms to reference standard
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (HPLC)	≥ 99.0% (High Purity Grade)
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.