Description

3-[2-({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}Amino)Phenyl]Propanoic Acid is a specialized Fmoc-protected amino acid derivative, a crucial building block in modern solid-phase peptide synthesis (SPPS). Its value lies in providing a protected amine group, enabling the precise, sequential construction of complex peptides and peptidomimetics. This high-purity intermediate is essential for researchers and manufacturers in pharmaceutical R&D, biotechnology, and fine chemical synthesis who require reliable, high-quality reagents for producing therapeutic peptides, diagnostic agents, and novel bioactive compounds. CAS No. 1702831-69-3.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected intermediate for the sequential assembly of peptide chains on resin supports.
• Pharmaceutical Research & Development: Used in the discovery and development of novel peptide-based therapeutics, including hormones, antibiotics, and enzyme inhibitors.
• Peptidomimetic Design: Serves as a building block for creating modified peptides with enhanced stability, bioavailability, or biological activity.
• Combinatorial Chemistry Libraries: Employed in the generation of diverse compound libraries for high-throughput screening against biological targets.
• Bioconjugation and Labeling: The reactive carboxylic acid group allows for conjugation to other molecules, carriers, or fluorescent tags.
• Academic and Institutional Research: A fundamental reagent in biochemistry and molecular biology laboratories studying protein structure-function relationships.

Basic Information

Item	Details
Product Name	3-[2-({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}Amino)Phenyl]Propanoic Acid
CAS No.	1702831-69-3
Molecular Formula	C24H21NO4
Molecular Weight	387.43 g/mol
Synonyms	Fmoc-2-Aminophenylpropionic Acid; Fmoc-2-Abz-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2-aminobenzenepropanoic Acid; Nα-Fmoc-2-aminohydrocinnamic acid; 3-[2-(Fmoc-amino)phenyl]propanoic acid; Fmoc-2-amino-β-phenylpropionic acid; (2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}phenyl)propanoic acid
EINECS	Contact for details

Quality Control

Our 3-[2-({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}Amino)Phenyl]Propanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide comprehensive Certificates of Analysis (COA) to ensure the material meets the stringent requirements for peptide synthesis and pharmaceutical research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under dry conditions, preferably with desiccant, to maintain stability and purity. For long-term storage, consider storage at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.