Description

3,3-Dimethyl-1-[(1R,4R)-4-(2-Hydroxyethyl)Cyclohexyl]Urea is a high-purity, stereochemically defined urea derivative with a chiral cyclohexyl backbone. This compound is a critical advanced intermediate in the synthesis of complex active pharmaceutical ingredients (APIs), particularly for chiral drug candidates. It is essential for research and development in pharmaceutical, agrochemical, and fine chemical industries where precise stereochemistry and functional group compatibility are paramount.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel chiral drug candidates, especially in metabolic and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of advanced, stereoselective pesticides and herbicides.
• Chiral Catalyst/ Ligand Synthesis: Serves as a precursor for creating sophisticated chiral auxiliaries and ligands used in asymmetric synthesis.
• Fine Chemical Production: Intermediate for high-value specialty chemicals requiring a defined (1R,4R) stereochemistry.
• Academic & Industrial R&D: A valuable tool for medicinal chemistry programs and process chemistry development in both academic and corporate settings.

Basic Information

Product Name	3,3-Dimethyl-1-[(1R,4R)-4-(2-Hydroxyethyl)Cyclohexyl]Urea
CAS No.	1698050-40-6
Molecular Formula	C11H22N2O2
Molecular Weight	214.31 g/mol
Synonyms	(1R,4R)-4-(2-Hydroxyethyl)cyclohexyl-3,3-dimethylurea; (1R,4R)-N-[4-(2-Hydroxyethyl)cyclohexyl]-N',N'-dimethylurea; 1-[(1R,4R)-4-(2-Hydroxyethyl)cyclohexyl]-3,3-dimethylurea; Urea, N-[(1R,4R)-4-(2-hydroxyethyl)cyclohexyl]-N,N-dimethyl-; (1R,4R)-4-(2-Hydroxyethyl)cyclohexyl dimethylurea
EINECS	Contact for details

Quality Control

Our 3,3-Dimethyl-1-[(1R,4R)-4-(2-Hydroxyethyl)Cyclohexyl]Urea is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.