Description

4-Chloro-2-Cyclopropyl-6-Fluoroquinazoline is a high-value, multi-functional quinazoline derivative serving as a critical building block in advanced organic synthesis. Its core value lies in its unique halogenated and cyclopropyl-substituted structure, which provides a versatile scaffold for constructing complex molecules with targeted biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly for oncology and antiviral therapies.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a monomer or functional additive in the research of advanced organic electronic materials and liquid crystals.
• Chemical Biology: Employed as a molecular probe or scaffold in medicinal chemistry for structure-activity relationship (SAR) studies.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.

Basic Information

Product Name	4-Chloro-2-Cyclopropyl-6-Fluoroquinazoline
CAS No.	1695621-65-8
Molecular Formula	C11H8ClFN2
Molecular Weight	222.65 g/mol
Synonyms	4-Chloro-2-cyclopropyl-6-fluoroquinazoline; 6-Fluoro-2-cyclopropyl-4-chloroquinazoline; 2-Cyclopropyl-4-chloro-6-fluoroquinazoline; Quinazoline, 4-chloro-2-cyclopropyl-6-fluoro-; 1695621-65-8; 4-Chloro-2-cyclopropyl-6-fluoro-quinazoline; 4-Chloro-2-cyclopropyl-6-fluorquinazolin
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Cyclopropyl-6-Fluoroquinazoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing purity, impurities, and full characterization data are provided with every shipment to support your R&D and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.