Description

8-Bromo-2-Chloromethyl-3H-Quinazolin-4-One is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is specifically engineered to serve as a key precursor in the development of novel pharmaceutical agents and agrochemicals. It is primarily sought after by research institutions and industrial R&D departments focused on medicinal chemistry, where it is used to construct complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical synthon for the synthesis of potential kinase inhibitors, anticancer agents, and other biologically active quinazolinone derivatives.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its halogenated quinazolinone core.
• Chemical Biology: Serves as a versatile scaffold for creating molecular probes and tool compounds to study enzyme function and biological pathways.
• Material Science: Investigated as a building block for specialty polymers and organic electronic materials due to its rigid, aromatic structure.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific projects requiring functionalized quinazolinones.

Basic Information

Product Name	8-Bromo-2-Chloromethyl-3H-Quinazolin-4-One
CAS No.	1694737-97-7
Molecular Formula	C9H6BrClN2O
Molecular Weight	273.51 g/mol
Synonyms	8-Bromo-2-(chloromethyl)-4(3H)-quinazolinone; 2-(Chloromethyl)-8-bromo-3H-quinazolin-4-one; 8-Bromo-2-chloromethylquinazolin-4(3H)-one; 4(3H)-Quinazolinone, 8-bromo-2-(chloromethyl)-; 1694737-97-7; 8-Br-2-CH2Cl-quinazolin-4-one
EINECS	Contact for details

Quality Control

Every batch of 8-Bromo-2-Chloromethyl-3H-Quinazolin-4-One is produced and tested under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.