Description

7-Bromospiro[Cyclopropane-1,3-Indoline] is a high-value, spirocyclic organic building block featuring a brominated indoline scaffold fused to a cyclopropane ring. This unique molecular architecture makes it a critical intermediate for the synthesis of complex, three-dimensional pharmacophores in modern drug discovery programs. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for constructing novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of spirocyclic drug candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used to develop novel herbicides and insecticides with potentially new modes of action, leveraging its constrained 3D structure.
• Chemical Biology Probe Synthesis: Serves as a scaffold for creating molecular probes to study enzyme function and protein-protein interactions.
• Material Science Precursor: Potential building block for advanced organic electronic materials due to its rigid, bromine-functionalized structure.
• Library Synthesis for High-Throughput Screening: Employed in parallel and combinatorial chemistry to generate diverse compound libraries for biological screening.

Basic Information

Product Name	7-Bromospiro[Cyclopropane-1,3-Indoline]
CAS No.	1694042-51-7
Molecular Formula	C10H8BrN
Molecular Weight	222.08 g/mol
Synonyms	7-Bromo-1-azaspiro[2.5]octa-1,4,6-trien-8-one; 7-Bromo-1-azaspiro[2.5]octa-4,6-dien-8-one; 7-Bromospiro[cyclopropane-1,3'-indolin]-2'-one; 7-Bromo-2,3-dihydrospiro[cyclopropane-1,3'-indol]-2'-one; 7-Bromo-1-azaspiro[2.5]oct-4,6-dien-8-one; 7-Bromospiro[indoline-3,1'-cyclopropan]-2-one
EINECS	Contact for details

Quality Control

Our 7-Bromospiro[Cyclopropane-1,3-Indoline] is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, guaranteeing traceability and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.