Description

(S)-3-(tert-Butyl)-4-(2,5-Diphenylcyclopenta-2,4-Dien-1-Yl)-2,3-Dihydrobenzo[D][1,3]Oxaphosphole CAS NO 1683581-58-9 is a high-purity, chiral organophosphorus compound characterized by its unique benzo[d][1,3]oxaphosphole core fused with a diphenylcyclopentadienyl moiety. This compound matters as a sophisticated ligand precursor or chiral auxiliary in asymmetric catalysis, enabling the synthesis of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel synthetic routes.

Application

• Asymmetric Catalysis: Serving as a chiral ligand or precursor for transition metal complexes in enantioselective C-C and C-X bond-forming reactions.
• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) requiring high stereochemical purity.
• Agrochemical Research: Used in developing novel, chiral pesticides and herbicides with improved efficacy and environmental profiles.
• Material Science: Potential monomer or additive for creating chiral polymers or advanced organic electronic materials.
• Academic & Industrial R&D: A valuable tool for methodological development in organic synthesis and catalysis studies.
• Process Chemistry: Evaluation and optimization for scalable manufacturing of chiral compounds under GMP-like conditions.

Basic Information

Product Name	(S)-3-(tert-Butyl)-4-(2,5-Diphenylcyclopenta-2,4-Dien-1-Yl)-2,3-Dihydrobenzo[D][1,3]Oxaphosphole
CAS No.	1683581-58-9
Molecular Formula	C29H27OP
Molecular Weight	422.50 g/mol
Synonyms	(S)-3-tert-Butyl-4-(2,5-diphenylcyclopenta-2,4-dien-1-yl)-2,3-dihydrobenzo[d][1,3]oxaphosphole; (S)-3-(tert-Butyl)-4-(2,5-diphenyl-1-cyclopenta-2,4-dienyl)-2,3-dihydro-1,3-benzoxaphosphole; (S)-HZ-01 Phosphole Ligand; Chiral Benzoxaphosphole Derivative; (S)-Configuration Phosphole; (S)-tBu-DPC-BOP; (S)-3-tert-Butyl-4-(2,5-diphenylcyclopentadienyl)benzo[d][1,3]oxaphosphole
EINECS	Contact for details

Quality Control

Our (S)-3-(tert-Butyl)-4-(2,5-Diphenylcyclopenta-2,4-Dien-1-Yl)-2,3-Dihydrobenzo[D][1,3]Oxaphosphole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for chiral purity and assay, NMR for structural confirmation, and elemental analysis, to ensure compliance with exacting R&D and process chemistry standards. Certificates of Analysis (COA) with detailed chromatographic data are provided for each shipment, supporting your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light). For long-term storage, consider inert atmosphere conditions to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.