Description

8-Bromo-4-Methylquinazoline is a high-purity brominated quinazoline derivative, a crucial building block in advanced organic synthesis. Its value lies in its versatile reactivity, particularly as a key intermediate for constructing complex heterocyclic systems and active pharmaceutical ingredients (APIs). This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to develop novel compounds with targeted properties.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly kinase inhibitors and other biologically active quinazoline-based molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging the quinazoline scaffold's bioactivity.
• Material Science: Acts as a building block for creating organic electronic materials, ligands for metal-organic frameworks (MOFs), and specialty polymers.
• Chemical Synthesis: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions to introduce complex functionalities.
• Academic & R&D: A valuable reagent for universities and contract research organizations (CROs) exploring new synthetic methodologies and compound libraries.

Basic Information

Product Name	8-Bromo-4-Methylquinazoline
CAS No.	1666113-01-4
Molecular Formula	C9H7BrN2
Molecular Weight	223.07 g/mol
Synonyms	4-Methyl-8-bromoquinazoline; 8-Bromo-4-methyl-quinazoline; Quinazoline, 8-bromo-4-methyl-; 1666113-01-4
EINECS	Contact for details

Quality Control

Our 8-Bromo-4-Methylquinazoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.