Description

n-(4-Pentynoyl)-Galactosamine Tetraacylated (Ac4Galnal) is a high-purity, synthetic monosaccharide derivative, specifically a peracetylated galactosamine analog functionalized with a terminal alkyne handle. This compound matters as a critical building block in chemical biology and glycochemistry, enabling site-specific conjugation via click chemistry reactions such as copper-catalyzed azide-alkyne cycloaddition (CuAAC). It is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors for applications including metabolic glycan labeling, probe development, and the synthesis of complex glycoconjugates and vaccines. CAS No. 1658458-26-4.

Application

• Metabolic Oligosaccharide Engineering (MOE): Used as a metabolic precursor for labeling and imaging cell-surface glycans.
• Click Chemistry Substrate: The terminal alkyne group facilitates efficient, bioorthogonal conjugation with azide-containing molecules for probe assembly.
• Glycoconjugate Synthesis: Serves as a key intermediate in the chemical and enzymatic synthesis of complex oligosaccharides and glycoproteins.
• Pharmaceutical Research: Employed in the development of carbohydrate-based vaccines, drug delivery systems, and therapeutic agents.
• Diagnostic Probe Development: Utilized to create fluorescent or affinity tags for detecting specific carbohydrate-mediated biological processes.
• Biomaterial Functionalization: Enables the surface modification of materials with bioactive carbohydrate motifs for tissue engineering and biosensing.

Basic Information

Product Name	n-(4-Pentynoyl)-Galactosamine Tetraacylated (Ac4Galnal)
CAS No.	1658458-26-4
Molecular Formula	C21H27NO10
Molecular Weight	453.44 g/mol
Synonyms	Ac4GalNAl; N-(4-Pentynoyl)-2-acetamido-2-deoxy-D-galactopyranose tetraacetate; Tetra-O-acetyl-N-pent-4-ynoyl-D-galactosamine; GalNAz tetraacetate alkyne; Peracetylated N-alkynyl galactosamine; 2-Acetamido-2-deoxy-D-galactose tetraacetate N-pentynoate; D-Galactosamine, N-(4-pentynoyl)-, tetraacetate
EINECS	Contact for details

Quality Control

Our n-(4-Pentynoyl)-Galactosamine Tetraacylated (Ac4Galnal) is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can support development under cGMP guidelines for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and light-sensitive; desiccants are recommended for long-term storage. Keep container tightly sealed under an inert atmosphere when not in use to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.