Description

Boc-4-(Trifluoromethoxy)-Dl-Phenylalanine CAS NO 1654772-46-9 is a protected amino acid derivative featuring a Boc (tert-butoxycarbonyl) protecting group and a trifluoromethoxy substituent on the phenyl ring. This compound is a critical building block in synthetic organic chemistry, enabling the controlled synthesis of complex peptides and modified amino acid structures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of peptide-based drugs and bioactive molecules targeting various therapeutic areas.
• Agrochemical Research: Used in creating novel pesticides and herbicides with enhanced activity and environmental stability.
• Peptide Synthesis: Serves as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis (SPPS).
• Chemical Biology Probes: Incorporation into peptides and proteins for studying biological mechanisms and protein-protein interactions.
• Material Science: Potential monomer for creating specialized polymers with unique surface properties and chemical resistance.
• Process Development: Used in route scouting and optimization for the commercial-scale production of fine chemicals.

Basic Information

Product Name	Boc-4-(Trifluoromethoxy)-Dl-Phenylalanine
CAS No.	1654772-46-9
Molecular Formula	C15H18F3NO5
Molecular Weight	349.30 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-4-(trifluoromethoxy)-DL-phenylalanine; Boc-4-(Trifluoromethoxy)phenylalanine; (RS)-2-((tert-Butoxycarbonyl)amino)-3-(4-(trifluoromethoxy)phenyl)propanoic acid; DL-Boc-4-Tfm-Phe-OH; N-Boc-4-(Trifluoromethoxy)DL-phenylalanine; tert-Butyl (RS)-(4-(trifluoromethoxy)benzyl)carbamate; Boc-DL-Phe(4-OCF3)-OH
EINECS	Contact for details

Quality Control

Our Boc-4-(Trifluoromethoxy)-Dl-Phenylalanine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.